GlyCol

Our premium, science-backed metabolic support formula designed to promote balanced blood sugar, healthy lipid profiles, optimized insulin response, weight management, and overall metabolic wellbeing—naturally supporting energy, heart health, and hormonal balance without synthetic additives.

At the core of GlyCol is Berbevis®, a premium, standardized berberine extract from the roots of Berberis aristata (traditionally used in Ayurvedic medicine), developed by Indena and enhanced with their proprietary Phytosome® technology. This advanced delivery system—incorporating pea proteins for better absorption, a more soluble berberine source, and grape seed extract for intestinal protection—delivers up to 10-fold improved bioavailability compared to standard berberine, superior efficacy, and excellent gastrointestinal tolerability, making GlyCol a highly effective, multi-target option for daily metabolic health.

• Supports Healthy Blood Sugar and Insulin Response: Favorably modulates insulin sensitivity, optimizes glucose levels, and helps maintain balanced blood sugar profiles—addressing key aspects of metabolic health in conditions like prediabetes or impaired fasting glucose.
• Promotes Balanced Lipid Profiles and Cardiovascular Health: Effectively reshapes lipid metabolism, supporting healthy total cholesterol, triglycerides, HDL levels, and blood vessel function while balancing risk factors like homocysteine—contributing to heart and vascular wellbeing.
• Aids Weight Management and Body Composition: Positively influences anthropometric parameters, reduces visceral fat, total fat mass, and waist circumference, and supports healthier fat-to-muscle ratios—especially when paired with diet and exercise.
• Enhances Hormonal Balance and Skin Health (e.g., in PCOS): In women with polycystic ovary syndrome, promotes resumption of regular menstruation (up to 70% vs. 16% control), normalizes ovarian anatomy (over 60% vs. 13%), improves acne (50% vs. 16%), reduces hirsutism, and alleviates skin discomforts while reducing low-grade chronic inflammation for better quality of life.
• Provides Multi-Target Metabolic and Anti-Inflammatory Support: Exerts a "Cloud Effect" by targeting multiple pathways (e.g., AMPK activation, mitochondrial function, gut microbiota modulation, oxidative stress reduction) to address root causes of metabolic imbalance, with strong antioxidant and pleiotropic benefits.

These benefits are backed by multiple peer-reviewed clinical studies, including double-blind, randomized, and open-label trials (e.g., published in Frontiers in Pharmacology 2023, Nutrients 2021, European Review for Medical and Pharmacological Sciences 2023, Minerva Gastroenterol 2024, and others). Key findings include significant improvements after 90 days to 6 months in subjects with metabolic concerns, hyperlipidemia, or PCOS—demonstrating superior outcomes over unformulated berberine in bioavailability (10x higher on molar basis with dose linearity), efficacy, and safety (well-tolerated, no major side effects or negative interactions). Preclinical in vitro and in vivo data further confirm its multi-target advantages.

By featuring Berbevis® as the key ingredient, GlyCol delivers a natural, clinically proven, high-absorption berberine solution for sustained metabolic balance, healthier body composition, and enhanced daily vitality.